CVE-2025-58757 | MONAI's unsafe use of Pickle deserialization may lead to RCE

Exp

MONAI (Medical Open Network for AI) is an AI toolkit for health care imaging. In versions up to and including 1.5.0, the `pickle_operations` function in `monai/data/utils.py` automatically handles dictionary key-value pairs ending with a specific suffix and deserializes them using `pickle.loads()` . This function also lacks any security measures. The deserialization may lead to code execution. As of time of publication, no known fixed versions are available.

Published: 2025-09-09 Last update: 2025-09-19 Assigner: [email protected] Source: [email protected]

Conclusion & alert: CVE-2025-58757 is rated High Exploit Risk (78.8/100): CVSS High severity, with medium exploitation likelihood (EPSS 1.39%). Core evidence: 1 public exploit reference(s) are indexed (Exploit-DB). Mandatory action: Public exploits are available—assess exposure, apply mitigations, and prioritize patching.

Risk is dynamic; we continuously reassess and refresh what is shown on this page as upstream context changes.

Public exploit references (Exploit-DB) for CVE-2025-58757

EDB-ID Source Kind Published Link
nvd_ref exploit_tag Exploit-DB ↗

Exploit prediction scoring system (EPSS) score for CVE-2025-58757

EPSS lead: Daily EPSS estimates relative likelihood of exploitation; percentile ranks this CVE among scored vulnerabilities (higher = more severe relative rank).

# Date Old EPSS score New EPSS score Delta (New - Old)
1 2026-06-04 1.06% 1.39% +0.34%
2 2026-05-25 0.69% 1.06% +0.37%
3 2026-05-14 0.69%

Full EPSS history (12 records total)

Common vulnerability scoring system (CVSS) metrics for CVE-2025-58757

CVSS metrics for this CVE.

Base score Version Severity Vector Exploitability Impact Score source
8.8 3.1 HIGH
CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H Click to expand
Attack vector (AV:N)
Could be attacked over the internet or any normal routed network—not just someone sitting at the machine.
Attack complexity (AC:L)
Once they can reach the bug, pulling it off is straightforward—no weird race conditions or rare setup.
Privileges required (PR:N)
No account or special rights needed—anonymous or random user is enough.
User interaction (UI:R)
A real person has to do something—click, install, enable—otherwise it doesn’t land.
Scope (S:U)
Damage stays in the same “trust bubble” as the broken component—no big spill into unrelated systems.
Confidentiality (C:H)
Serious risk that confidential data gets exposed in a big way.
Integrity (I:H)
They could widely tamper with or forge data—trust in the data is badly hurt.
Availability (A:H)
Could take the service down hard or make it unusable for people who depend on it.
2.8 5.9 [email protected]

Weakness enumeration for CVE-2025-58757

GitHub Security Advisory for CVE-2025-58757

GHSA-p8cm-mm2v-gwjm · Severity: high · Ecosystem: pip — Monai: Unsafe use of Pickle deserialization may lead to RCE

Affected software / configurations for CVE-2025-58757

Vendor Product Version Raw CPE
monai medical_open_network_for_ai <= 1.5.0 cpe:2.3:a:monai:medical_open_network_for_ai:*:*:*:*:*:*:*:*

References for CVE-2025-58757

cvelogic Threat Intelligence