CVE-2026-31973 | NULL pointer dereference in samtools cram-size

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the `cram_decode_compression_header()` was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Published: 2026-03-18 Last update: 2026-06-17 Assigner: [email protected] Source: [email protected]
NVD Status：Analyzed，CVE State: published
View at NVD, CVE.org, EUVD

CVE-2026-31973 is rated Moderate Risk (42.1/100): CVSS Medium severity, with low exploitation likelihood (EPSS 0.52%). Review affected assets and schedule remediation.

Risk is dynamic; we continuously reassess and refresh what is shown on this page as upstream context changes.

Exploit prediction scoring system (EPSS) score for CVE-2026-31973

EPSS lead: Daily EPSS estimates relative likelihood of exploitation; percentile ranks this CVE among scored vulnerabilities (higher = more severe relative rank).

# Date Old EPSS score New EPSS score Delta (New - Old)
1 2026-06-15 0.01% 0.52% +0.51%
2 2026-03-19 — 0.01% —

Full EPSS history (2 records total)

Common vulnerability scoring system (CVSS) metrics for CVE-2026-31973

CVSS metrics for this CVE.

Base score Version Severity Vector Exploitability Impact Score source
6.9 4.0 MEDIUM
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:L/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X Click to expand
Attack vector (AV:N)
Could be attacked over the internet or any normal routed network.
Attack complexity (AC:L)
Exploitation conditions are straightforward and stable.
Attack requirements (AT:N)
No additional preconditions are required beyond normal reachability.
Privileges required (PR:N)
No privileges are required.
User interaction (UI:N)
No user interaction is required.
Vulnerable system confidentiality impact (VC:N)
No confidentiality impact on the vulnerable system.
Vulnerable system integrity impact (VI:L)
Limited integrity impact on the vulnerable system.
Vulnerable system availability impact (VA:L)
Limited availability impact on the vulnerable system.
Subsequent system confidentiality impact (SC:N)
No confidentiality impact on subsequent systems.
Subsequent system integrity impact (SI:N)
No integrity impact on subsequent systems.
Subsequent system availability impact (SA:N)
No availability impact on subsequent systems.
Exploit maturity (threat) (E:X)
Not defined: no reliable threat intelligence; scoring assumes the worst case (equivalent to Attacked).
Confidentiality requirement (CR:X)
Not defined: insufficient information; scoring treats this like High (worst case).
Integrity requirement (IR:X)
Not defined: insufficient information; scoring treats this like High (worst case).
Availability requirement (AR:X)
Not defined: insufficient information; scoring treats this like High (worst case).
Modified attack vector (MAV:X)
Not defined: scoring uses the Base Attack Vector (AV).
Modified attack complexity (MAC:X)
Not defined: scoring uses the Base Attack Complexity (AC).
Modified attack requirements (MAT:X)
Not defined: scoring uses the Base Attack Requirements (AT).
Modified privileges required (MPR:X)
Not defined: scoring uses the Base Privileges Required (PR).
Modified user interaction (MUI:X)
Not defined: scoring uses the Base User Interaction (UI).
Modified vulnerable system confidentiality impact (MVC:X)
Not defined: scoring uses the Base VC metric.
Modified vulnerable system integrity impact (MVI:X)
Not defined: scoring uses the Base VI metric.
Modified vulnerable system availability impact (MVA:X)
Not defined: scoring uses the Base VA metric.
Modified subsequent system confidentiality impact (MSC:X)
Not defined: scoring uses the Base SC metric.
Modified subsequent system integrity impact (MSI:X)
Not defined: scoring uses the Base SI metric.
Modified subsequent system availability impact (MSA:X)
Not defined: scoring uses the Base SA metric.
Safety (supplemental) (S:X)
Not evaluated.
Automatable (supplemental) (AU:X)
Not evaluated.
Recovery (supplemental) (R:X)
Not evaluated.
Value density (supplemental) (V:X)
Not evaluated.
Vulnerability response effort (supplemental) (RE:X)
Not evaluated.
Provider urgency (supplemental) (U:X)
Not evaluated.
 — — [email protected]
7.5 3.1 HIGH
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:H Click to expand
Attack vector (AV:N)
Could be attacked over the internet or any normal routed network—not just someone sitting at the machine.
Attack complexity (AC:L)
Once they can reach the bug, pulling it off is straightforward—no weird race conditions or rare setup.
Privileges required (PR:N)
No account or special rights needed—anonymous or random user is enough.
User interaction (UI:N)
Nobody has to click “OK” or open a trap file; it can work without a victim helping.
Scope (S:U)
Damage stays in the same “trust bubble” as the broken component—no big spill into unrelated systems.
Confidentiality (C:N)
Doesn’t really leak secrets in a meaningful way.
Integrity (I:N)
Data isn’t meaningfully altered or forged.
Availability (A:H)
Could take the service down hard or make it unusable for people who depend on it.
 3.9 3.6 [email protected]

Weakness enumeration for CVE-2026-31973

OS Trackers for CVE-2026-31973

vendor priority summary link
debian unimportant CVE-2026-31973 unimportant priority: Debian including 1 source packages (samtools), 5 status rows across 5 suites (bookworm, bullseye, forky, sid, trixie): open 5. https://security-tracker.debian.org/tracker/CVE-2026-31973
ubuntu medium CVE-2026-31973 medium priority: Ubuntu including 1 source packages (samtools), 8 status rows across 8 suites (bionic, focal, jammy, noble, questing, trusty, upstream, xenial): needs-triage 8. https://ubuntu.com/security/CVE-2026-31973

Affected software / configurations for CVE-2026-31973

Vendor Product Version Raw CPE
samtools samtools >= 1.17, <= 1.21.1 cpe:2.3:a:samtools:samtools:*:*:*:*:*:*:*:*
samtools samtools >= 1.22, < 1.22.2 cpe:2.3:a:samtools:samtools:*:*:*:*:*:*:*:*
samtools samtools 1.23 cpe:2.3:a:samtools:samtools:1.23:*:*:*:*:*:*:*

References for CVE-2026-31973

cvelogic Threat Intelligence