CVE-2025-54808 | Oxford Nanopore Technologies MinKNOW Insufficiently Protected Credentials

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Published: 2025-10-23 Last update: 2026-04-15 Assigner: [email protected] Source: [email protected]
NVD Status：Deferred，CVE State: published
View at NVD, CVE.org, EUVD

CVE-2025-54808 is rated Low Risk (30.8/100): CVSS High severity, with low exploitation likelihood (EPSS 0.02%). Monitor for updates and reassess as exploit intelligence or EPSS changes.

Risk is dynamic; we continuously reassess and refresh what is shown on this page as upstream context changes.

Exploit prediction scoring system (EPSS) score for CVE-2025-54808

EPSS lead: Daily EPSS estimates relative likelihood of exploitation; percentile ranks this CVE among scored vulnerabilities (higher = more severe relative rank).

# Date Old EPSS score New EPSS score Delta (New - Old)
1 2025-10-24 — 0.02% —

Full EPSS history (1 record total)

Common vulnerability scoring system (CVSS) metrics for CVE-2025-54808

CVSS metrics for this CVE.

Base score Version Severity Vector Exploitability Impact Score source
7.3 4.0 HIGH
CVSS:4.0/AV:L/AC:L/AT:P/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X Click to expand
Attack vector (AV:L)
Attacker needs local access on the target system.
Attack complexity (AC:L)
Exploitation conditions are straightforward and stable.
Attack requirements (AT:P)
Additional preconditions must be present for exploitation.
Privileges required (PR:L)
Low privileges are required.
User interaction (UI:N)
No user interaction is required.
Vulnerable system confidentiality impact (VC:H)
High confidentiality impact on the vulnerable system.
Vulnerable system integrity impact (VI:H)
High integrity impact on the vulnerable system.
Vulnerable system availability impact (VA:H)
High availability impact on the vulnerable system.
Subsequent system confidentiality impact (SC:N)
No confidentiality impact on subsequent systems.
Subsequent system integrity impact (SI:N)
No integrity impact on subsequent systems.
Subsequent system availability impact (SA:N)
No availability impact on subsequent systems.
Exploit maturity (threat) (E:X)
Not defined: no reliable threat intelligence; scoring assumes the worst case (equivalent to Attacked).
Confidentiality requirement (CR:X)
Not defined: insufficient information; scoring treats this like High (worst case).
Integrity requirement (IR:X)
Not defined: insufficient information; scoring treats this like High (worst case).
Availability requirement (AR:X)
Not defined: insufficient information; scoring treats this like High (worst case).
Modified attack vector (MAV:X)
Not defined: scoring uses the Base Attack Vector (AV).
Modified attack complexity (MAC:X)
Not defined: scoring uses the Base Attack Complexity (AC).
Modified attack requirements (MAT:X)
Not defined: scoring uses the Base Attack Requirements (AT).
Modified privileges required (MPR:X)
Not defined: scoring uses the Base Privileges Required (PR).
Modified user interaction (MUI:X)
Not defined: scoring uses the Base User Interaction (UI).
Modified vulnerable system confidentiality impact (MVC:X)
Not defined: scoring uses the Base VC metric.
Modified vulnerable system integrity impact (MVI:X)
Not defined: scoring uses the Base VI metric.
Modified vulnerable system availability impact (MVA:X)
Not defined: scoring uses the Base VA metric.
Modified subsequent system confidentiality impact (MSC:X)
Not defined: scoring uses the Base SC metric.
Modified subsequent system integrity impact (MSI:X)
Not defined: scoring uses the Base SI metric.
Modified subsequent system availability impact (MSA:X)
Not defined: scoring uses the Base SA metric.
Safety (supplemental) (S:X)
Not evaluated.
Automatable (supplemental) (AU:X)
Not evaluated.
Recovery (supplemental) (R:X)
Not evaluated.
Value density (supplemental) (V:X)
Not evaluated.
Vulnerability response effort (supplemental) (RE:X)
Not evaluated.
Provider urgency (supplemental) (U:X)
Not evaluated.
 — — [email protected]
7.8 3.1 HIGH
CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H Click to expand
Attack vector (AV:L)
They already need access on the box, or another person has to do something wrong; it’s not a remote drive-by.
Attack complexity (AC:L)
Once they can reach the bug, pulling it off is straightforward—no weird race conditions or rare setup.
Privileges required (PR:L)
A normal user session is enough; they don’t have to be admin.
User interaction (UI:N)
Nobody has to click “OK” or open a trap file; it can work without a victim helping.
Scope (S:U)
Damage stays in the same “trust bubble” as the broken component—no big spill into unrelated systems.
Confidentiality (C:H)
Serious risk that confidential data gets exposed in a big way.
Integrity (I:H)
They could widely tamper with or forge data—trust in the data is badly hurt.
Availability (A:H)
Could take the service down hard or make it unusable for people who depend on it.
 1.8 5.9 [email protected]

Weakness enumeration for CVE-2025-54808

Affected software / configurations for CVE-2025-54808

Vendor Product Version Raw CPE
No affected products in dataset.

References for CVE-2025-54808

cvelogic Threat Intelligence